The Concept Of Dose Toxicity

Lately I’ve seen some misunderstanding regarding the concept of “dose.” Our predecessors once said “sola dosis facit venenum” which translates to “the dose makes the poison.” That concept still holds true today. Unfortunately, the modern anti-science movement seems to have forgotten that.

Sometimes anti-vaxxers like to crow about the few atoms of mercury present in some vaccines. Other times its anti-fluoride activists complaining that fluoride is added to the municipal water supplies in barrels that would be dangerous to drink from. There’s a rather famous meme that summarizes this idea pretty well but it doesn’t make sense to some people.

Here’s an example that will hopefully make things make more sense:

At a high enough concentration, most things are deadly. Let’s look at apples.

This is actually a pear rather than an apple as previously stated. Thanks Matt S. for pointing that out. Pears contain 60 mg of formaldehyde so the example still works out.

Apples contain formaldehyde. This is used in embalming, is a known carcinogen, and is fatal at levels in mice at 42mg/kg.

You eat apples every day. Some would say that is sufficient to ward away doctors.

The EPA has determined a safe level of consuming formaldehyde at 0.2mg/kg per day for humans.

There is No Observable Adverse Effect Level (NOAEL) below that continual dosage. That means you won’t be injured by it under worst-case conditions.

Apples contain a very small amount of formaldehyde (about 1mg per apple).

I weigh about 77kg. That’s healthy, I think. That means I could consume 15.4mg of formaldehyde per day every day and be expected to suffer no ill effects over my life from that chemical.

I could eat 15 apples in a given day and still suffer no adverse effects from formaldehyde in the apple. That’d give me 15mg for the 77kg I weigh for a total of 0.19mg/kg effective dose. I could do this every day and still be fine. I might have a tummy ache from eating so many apples but I wouldn’t be poisoned from that one chemical.

Similarly, fluoride can cause harm at extremely large doses in a very short amount of time. It is not possible to come remotely close to that by drinking fluoridated water. You would first die from overhydration as your liver fails or as your cellular tissue ruptures from over hydration.

4 Responses

  1. Jonathan Brandt
    Jonathan Brandt at |

    At least we know that 100 vaccines a day will keep a doctor away!

  2. truluv4u
    truluv4u at |

    As an engineer (like my own husband), you should be able to easily do the math regarding the collective quantities of aluminum in a typical round of combined doses given to a young child. Please view this link and consider the real toxicity issues of defenseless children who are given 49+ vaccine doses by the age of six. .

  3. truluv4u
    truluv4u at |

    Please view my response to your post on the link you provided.


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